Concepedia

A magnetic micropore chip for rapid (<1 hour) unbiased circulating tumor cell isolation and in situ RNA analysis

Jina Ko, Neha Bhagwat, Stephanie S. Yee, Taylor A. Black, Colleen Redlinger, Janae Romeo, Mark H. O’Hara, Arjun Raj, Erica L. Carpenter, Ben Z. Stanger,

Lab on a Chip · 2017 · 42 citations · 45 references

DOI

Concepts

Abstract

We have developed a microchip platform that combines fast, magnetic micropore based negative selection (&gt;10 mL h<sup>−1</sup>) with rapid on-chip<italic>in situ</italic>RNA profiling.

References

45

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Spatially resolved, highly multiplexed RNA profiling in single cells

Kok Hao Chen, Alistair N. Boettiger, Jeffrey R. Moffitt et al. · Science · 2015 · 3.1K citations · Full text

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Tumor Cells Circulate in the Peripheral Blood of All Major Carcinomas but not in Healthy Subjects or Patients With Nonmalignant Diseases

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Arjun Raj, Patrick van den Bogaard, Scott A. Rifkin et al. · Nature Methods · 2008 · 2.2K citations · Full text

, , +12