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An implantable 700μW 64-channel neuromodulation IC for simultaneous recording and stimulation with rapid artifact recovery
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2017
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EngineeringAnalog DesignHv Cmos IcBiomedical EngineeringNeurochipRapid Artifact RecoveryStimulation DeviceNeuromodulationMixed-signal Integrated CircuitNeurologySimultaneous RecordingConcurrent Neural StimulationNeurorehabilitationNeuromodulation (Medicine)Implantable 700μWComputer EngineeringNeurostimulationNeural InterfaceNeurophysiologyBioelectronicsArtifact RecoveryNeuroscienceElectrophysiologyCentral Nervous SystemMedicine
We present an 180nm HV CMOS IC for concurrent neural stimulation and recording that combines 64 low-noise recording front-ends and 4 independent stimulators multiplexed to any of the 64 channels. The stimulators have 5mA peak current, 12V compliance and dynamic power management to maximize efficiency. Co-design of the stimulation and recording subsystems resulted in 100mV of recording linear range, 70nV/rtHz noise, and a rapid 1ms (single-sample) artifact recovery during stimulation.