Effect of flavonoid-containing extracts on the growth of transplanted sarcoma 45, peripheral blood and bone marrow condition after oral and intramuscular administration in rats

Abstract

Introduction Oncological diseases take one of the leading places in the structure of mortality all over the world. For a long time it was believed that bioflavonoids with a broad spectrum of pharmacological activity are not very perspective in terms of antitumor activity. In 2011 the apoptosis-inducing effect of plant flavonoid Vagonin was discovered in tumor cells [1, 2].