<scp>CD</scp>4+ Cell infiltration into subcutaneous adipose tissue is not indicative of productively infected cells during acute <scp>SHIV</scp> infection

Abstract

Limited longitudinal data exist on the effect of HIV on adipose tissue (AT). We found an increase in CD4+ cells and detectable SHIV-RNA in AT during acute SHIV infection. SHIV-RNA+ cells were rare, suggesting that AT is unlikely to be a major source of productively infected cells in SHIV infection.