Diversity of endophytic actinomycetes from Karangkadu mangrove ecosystem and its antibacterial potential against bacterial pathogens

Abstract

A total of 17 actinomycetes isolates were identified from leaves of 5 different halophytic plants such as Avicennia marina, Bruguiera cylindrica, Rhizophora mucronata, Salicornia brachiata and Suaeda monoica and tested for antibacterial activity against some bacterial pathogens. Preliminary test indicated that, 10 isolates showed high sensitivity against at least one of the pathogens. In secondary screening, cell free crude extract from ACT1 isolate exhibited maximum (13±1.12 mm) zone of inhibition against antibiotic resistant pathogen (Klebsiella sp.). The endophytic actinomycetes isolated with persistent antibacterial activity from Karangkadu mangrove ecosystem could be a potential source for the exploration of novel antibacterial metabolites for the safe treatment of bacterial diseases.