Thromboembolic Risk, Bleeding Outcomes and Effect of Different Antithrombotic Strategies in Very Elderly Patients With Atrial Fibrillation: A Sub‐Analysis From the PREFER in AF ( <i>PRE</i> vention o <i>F</i> Thromboembolic Events– <i>E</i> uropean <i>R</i> egistry in <i>A</i> trial <i>F</i> ibrillation)

Abstract

Because the risk of stroke increases with age more than the risk of bleeding, the absolute benefit of OAC is highest in very elderly patients, where it, by far, outweighs the risk of bleeding, with the greatest net clinical benefit in such patients.