Concepedia

Publication | Open Access

Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA Nephropathy

DOIFull Paper Access

58

Citations

51

References

2017

Year

Koshi Yamada, Zhiqiang Huang, Milan Raška, Colin Reily, Joshua C. Anderson, Hitoshi Suzuki, Hiroyuki Ueda, Zina Moldoveanu, Krzysztof Kiryluk, Yusuke Suzuki,
Kidney International Reports

Abstract

Our results revealed that IL-6-induced aberrant activation of STAT3-mediated overproduction of galactose-deficient IgA1. STAT3 signaling pathway may thus represent a new target for disease-specific therapy of IgA nephropathy.

References

YearCitations

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