“On water” synthesis of dibenzo-[1,4]-diazepin-1-ones using<scp>l</scp>-proline as an organocatalyst and under catalyst-free conditions, and their evaluation as α-glucosidase inhibitors

Abstract

Functionalized dibenzo-[1,4]-diazepin-1-ones are synthesized using the “on-water” concept in the presence of<sc>l</sc>-proline (organocatalyst; 20 mol%) and under catalyst free conditions (sealed tube) in an aqueous medium.