Stimulation of functional neuronal regeneration from Müller glia in adult mice

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

Cole Trapnell, Davide Cacchiarelli, Jonna Grimsby et al. · Nature Biotechnology · 2014 · 7.8K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +16

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

Jason D. Buenrostro, Paul G. Giresi, Lisa C. Zaba et al. · Nature Methods · 2013 · 7K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

GREAT improves functional interpretation of cis-regulatory regions

Cory Y. McLean, Dave Bristor, Michael Hiller et al. · Nature Biotechnology · 2010 · 5K citations

Life Sciences, Bioinformatics, Molecular Biology +12

BEDOPS: high-performance genomic feature operations

Shane Neph, Michael S. Kuehn, Alex Reynolds et al. · Bioinformatics · 2012 · 1.2K citations · Full text

Medicine, Bioinformatics, High-performance Computing +10

In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model

Ziyuan Guo, Lei Zhang, Zheng Wu et al. · Cell stem cell · 2013 · 833 citations · Full text

Medicine, Neurobiology, Neuroscience +17