Clinical Infectious Diseases · 2017 · 163 citations · 3 references
Life SciencesInfectious DiseasesMicrobiologyAntimicrobial ResistanceMedical MicrobiologyMicrobiome ResearchAntibiotic ResistanceFecal Microbiota TransplantationMicrobiome TherapeuticsRecurrent Urinary Tract InfectionUrinary Tract Infection PreventionUrinary Tract InfectionsAntibiotic Resistance ProfilingAntibiotic Susceptibility Data AnalysisAntibiotic Susceptibility TestingGut Microbiome AlterationsGut Microbiome DysbiosisRecurrent Clostridioides Difficile InfectionRecurrent Urinary Tract Infection ProphylaxisUrinary Tract Infection Antibiotic Therapy
Broad-spectrum antibiotics for recurrent multidrug-resistant urinary tract infections (UTIs) disrupt the gut microbiome and promote antibiotic resistance. Fecal microbiota transplantation led to resolution of recurrent Clostridium difficile, significantly decreased recurrent UTI frequency, and improved antibiotic susceptibility profile of UTI-causing organisms.
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Burden of <i>Clostridium difficile</i> Infection in the United States
Fernanda C. Lessa, Yi Mu, Wendy Bamberg et al. · New England Journal of Medicine · 2015 · 2.6K citations · Full text
Erik R. Dubberke, Kathleen M. Mullane, Dale N. Gerding et al. · Open Forum Infectious Diseases · 2016 · 76 citations · Full text