P2X receptors up-regulate the cell-surface expression of the neuronal glycine transporter GlyT2

Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons

Carolyn J. Lewis, S. Neidhart, C. Holy et al. · Nature · 1995 · 1K citations

Life Sciences, Molecular Biology, Neuroscience +13

Kinetic Analysis of Secretory Protein Traffic and Characterization of Golgi to Plasma Membrane Transport Intermediates in Living Cells

Koret Hirschberg, Chad M. Miller, Jan Ellenberg et al. · The Journal of Cell Biology · 1998 · 608 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Glycine transporters are differentially expressed among CNS cells

Francisco Zafra, Carmen Aragón, Luis Olivares et al. · Journal of Neuroscience · 1995 · 524 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study

Rayid Abdulqawi, Rachel Dockry, Kimberley Holt et al. · The Lancet · 2014 · 483 citations

Medicine, Pharmacology, Pharmacotherapy +10

A-317491, a novel potent and selective non-nucleotide antagonist of P2X ₃ and P2X _2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat

Michael F. Jarvis, Edward C. Burgard, Steve McGaraughty et al. · Proceedings of the National Academy of Sciences · 2002 · 466 citations

Medicine, Neurobiology, Pharmacology +17