Concepedia

P2Y<sub>12 </sub>and P2Y<sub>13</sub> receptors involved in ADPβs induced the release of IL-1β, IL-6 and TNF-α from cultured dorsal horn microglia

Pei-Wen Liu, Ming-Xia Yue, Rui Zhou, Juan Niu, Dujuan Huang, Tao Xu, Pei Luo, Xiaohong Liu, Junwei Zeng

Journal of Pain Research · 2017 · 45 citations · 66 references

DOIFull text

Open access

Abstract

These observations suggest that P2Y<sub>12</sub> and P2Y<sub>13</sub> receptor-evoked gene expression and release of IL-1β, IL-6 and TNF-α are associated with ROCK/P38MAPK/NF-κb signaling pathway.

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