Pretreatment with paricalcitol attenuates level and expression of matrix metalloproteinases in a rat model of renal ischemia-reperfusion injury - Concepedia

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Pretreatment with paricalcitol attenuates level and expression of matrix metalloproteinases in a rat model of renal ischemia-reperfusion injury

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2017

Year

Sibel Ersan, Mehmet Tanrısev, Zahide Çavdar, Mehtat Ünlü, Ayşe Koçak, Cemre Ural, Timur Köse

Clinical Nephrology

Abstract

Paricalcitol may attenuate renal tubular injury caused by IRI by decreasing both level and expression of MMPs. Further studies are required to investigate the interplay between activated vitamin D and MMPs in AKI. .