Concepedia

<i>Helicobacter pylori</i>vacA genotype is a predominant determinant of immune response to<i>Helicobacter pylori</i>CagA

Alexander Link, Cosima Langner, Wiebke Schirrmeister, Wiebke Habendorf, Jochen Weigt, Marino Venerito, Ina Tammer, Dirk Schlüter, Philipp Schlaermann, Thomas F. Meyer,

World Journal of Gastroenterology · 2017 · 35 citations · 32 references

DOIFull text

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Concepts

Abstract

AIM: CagA-immune response. METHODS: CagA protein expression and IL-8 induction in co-cultivation model with AGS cells. RESULTS: as major co-determinant of the immune response. CONCLUSION: polymorphism, suggesting the crucial role of bacterial factors in immune and clinical phenotype of the infection.

References

32

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