Concepedia

Rac1-mediated cardiac damage causes diastolic dysfunction in a mouse model of subacute doxorubicin-induced cardiotoxicity

Jan Ohlig, Christian Henninger, Simone Zander, Marc W. Merx, Malte Kelm, Gerhard Fritz

Archives of Toxicology · 2017 · 27 citations · 31 references

DOI

Concepts

References

31

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

Yuan Gao, J. Bradley Dickerson, Fukun Guo et al. · Proceedings of the National Academy of Sciences · 2004 · 1.1K citations · Full text

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Anthracycline-Induced Cardiomyopathy

Daniela Cardinale, Alessandro Colombo, Giuseppina Lamantia et al. · Journal of the American College of Cardiology · 2010 · 1.1K citations

Cardiac Toxicity 4 to 20 Years After Completing Anthracycline Therapy

Laurel J. Steinherz · JAMA · 1991 · 966 citations

, , +16

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins.

Rosario Perona, Silvia Montaner, Luisa Saniger et al. · Genes & Development · 1997 · 615 citations · Full text

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Topoisomerase IIβ–Mediated DNA Double-Strand Breaks: Implications in Doxorubicin Cardiotoxicity and Prevention by Dexrazoxane

Yi Lisa Lyu, John E. Kerrigan, Chao‐Po Lin et al. · Cancer Research · 2007 · 610 citations

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