Concepedia

Publication | Open Access

Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis

DOIFull Paper Access

107

Citations

34

References

2017

Year

Anusha N. Seneviratne, Andreas Edsfeldt, Jennifer E. Cole, Christina Kassiteridi, Maarten Swart, Inhye Park, Patricia Green, Tariq Khoyratty, David Saliba, Michael E. Goddard,
Circulation

Abstract

IRF5 is detrimental in atherosclerosis by promoting the maintenance of proinflammatory CD11c<sup>+</sup> macrophages within lesions and controlling the expansion of the necrotic core by impairing efferocytosis.

References

YearCitations

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