An experimental study of analgesic activity of Cissus quadrangularis

Abstract

1. The analgesic activity of alcoholic extract of whole plant of cissus quadrangularis family vitaceae), was studied in mice by Haffner's Clip and Eddy's hot plate methods. 2. The extract effective by both oral and i.p. routes significantly (P < 0.001) increased the reaction time by both methods. 3. The duration of analgesic activity was from 2 to 4 h and optimum effect was observed at l/20th -1/10th of LD50 dose. The extract compared well with acetylsalicylic acid.