New endeavours involving the cooperative behaviour of TMAO and urea towards the globular state of poly(N-isopropylacrylamide)

Abstract

Studies have provided evidence for the destruction of the hydrogen bonds of poly(<italic>N</italic>-isopropylacrylamide) (PNIPAM) in the presence of osmolytes such as trimethylamine <italic>N</italic>-oxide (TMAO) and urea.