Concepedia

Astragalus polysaccharides inhibits cell growth and pro-inflammatory response in IL-1β-stimulated fibroblast-like synoviocytes by enhancement of autophagy via PI3K/AKT/mTOR inhibition

Qingliang Meng, Xuzhao Du, Huilian Wang, Huimin Gu, Junping Zhan, Zipeng Zhou

APOPTOSIS · 2017 · 66 citations · 29 references

DOI

Concepts

References

29

Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway

Dhruv Kumar, Sharmila Shankar · Cancer Letters · 2013 · 219 citations

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Antitumor and immunomodulatory activity of Astragalus membranaceus polysaccharides in H22 tumor-bearing mice

Bin Yang, Bing Xiao, Taoyu Sun · International Journal of Biological Macromolecules · 2013 · 201 citations

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Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction

Thomas Pap, Juliane K. Franz, Klaus M. Hummel et al. · Arthritis Research & Therapy · 1999 · 177 citations · Full text

Antioxidant activity of Astragalus polysaccharides and antitumour activity of the polysaccharides and siRNA

Rui Li, Weichang Chen, Weipeng Wang et al. · Carbohydrate Polymers · 2010 · 156 citations

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Tumor Necrosis Factor α Induces Sustained Signaling and a Prolonged and Unremitting Inflammatory Response in Rheumatoid Arthritis Synovial Fibroblasts

Angela Lee, Yu Qiao, Galina Grigoriev et al. · Arthritis & Rheumatism · 2013 · 144 citations · Full text