Decreased calcium flux in Niemann-Pick type C1 patient-specific iPSC-derived neurons due to higher amount of calcium-impermeable AMPA receptors

A new mathematical model for relative quantification in real-time RT-PCR

Michael W. Pfaffl · Nucleic Acids Research · 2001 · 34.9K citations · Full text

Life Sciences, Molecular Biology, Gene Expression +12

Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol Homeostasis

Eugene D. Carstea, Jill A. Morris, Katherine Coleman et al. · Science · 1997 · 1.5K citations

Life Sciences, Genetics, Molecular Biology +17

Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells

Miguel A. Esteban, Tao Wang, Baoming Qin et al. · Cell stem cell · 2010 · 972 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +14

Lipid Rafts in the Maintenance of Synapses, Dendritic Spines, and Surface AMPA Receptor Stability

Heike Hering, Chih-Chun Lin, Morgan Sheng · Journal of Neuroscience · 2003 · 587 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Topological Analysis of Niemann-Pick C1 Protein Reveals That the Membrane Orientation of the Putative Sterol-sensing Domain Is Identical to Those of 3-Hydroxy-3-methylglutaryl-CoA Reductase and Sterol Regulatory Element Binding Protein Cleavage-activating Protein

Joanna P. Davies, Yiannis A. Ioannou · Journal of Biological Chemistry · 2000 · 301 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17