ACROMEGALY AND THE HEART: A CLINICAL AND PATHOLOGIC STUDY

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Article1 June 1951ACROMEGALY AND THE HEART: A CLINICAL AND PATHOLOGIC STUDYMILTON R. HEJTMANCIK, M.D., JAMES Y. BRADFIELD JR., M.D., GEORGE R. HERRMANN, M.D., F.A.C.P.MILTON R. HEJTMANCIK, M.D., JAMES Y. BRADFIELD JR., M.D., GEORGE R. HERRMANN, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-34-6-1445 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHeart disease has long been known as a frequent complicating factor and a common cause of exitus in acromegaly. Only nine years after the recognition of the features of acromegaly by Marie1in 1886, Huchard2reported cardiac enlargement in the clinical and autopsy findings of three patients with the disease. Fournier3drew particular attention to the features of cardiac failure in a series of 25 patients, pointing out the frequent association of cardiomegaly with hypertrophy of all the viscera. Similar reports, consisting usually of one or two cases, have appeared from time to time in the French and German literature,...Bibliography1. Marie P: Sur deux cas d'acromégalie; hypertrophie singulière non congénitale des extrémités supérieures, inférieures et céphalique, Rev. de méd., Par. 6: 297-333, 1886. Google Scholar2. Huchard H: Anatomie pathologique, lésions et troubles cardiovasculaires de l'acromégalie, J. d. praticiens 9: 249, 1895. Google Scholar3. Fournier JB: Acromegalie et troubles cardiovasculaires, Thesis, Paris, No. 3, 1896. Google Scholar4. CourvilleMason CVR: The heart in acromegaly, Arch. Int. Med. 61: 704-713, 1938. CrossrefGoogle Scholar5. HumphryDixon LWE: A case of acromegaly with hypertrophied heart; pressor substances in the urine, Brit. M. J. 2: 1047-1049, 1910. Google Scholar6. Hinsdale G: Acromegaly, 1898, William M. Warren, Detroit. Google Scholar7. CushingDavidoff HLM: The pathologic findings in four autopsied cases of acromegaly, with a discussion of their significance, Monograph 22, Rockefeller Institute for Medical Research, 1927, pp. 1-121. Google Scholar8. Davidoff LM: Studies in acromegaly. III. The anamnesis and symptomatology in one hundred cases, Endocrinology 10: 461-483, 1926. CrossrefGoogle Scholar9. Bartelheimer H: Kreislaufbesonderheiten bei der Akromegalie, Deutsch. med. Wchnschr. 72: 382-385, 1947. CrossrefMedlineGoogle Scholar10. Amsler C: Zur Lehre der Splanchnomegalie bei Akromegalie, Berl. klin. Wchnschr. 49: 1600-1604, 1912. Google Scholar11. Kraus JE: Morphologic aspects and genesis of disorders of the adenohypophysis, Arch. Path. 40: 191-207, 1945. Google Scholar12. GoldbergLisser MBH: Acromegaly: a consideration of its course and treatment. Report of four cases with autopsies, J. Clin. Endocrinol. 2: 477-501, 1942. CrossrefGoogle Scholar13. Sternberg M: Acromegaly, translated by F. R. B. Atkinson, 1899, H. K. Lewis, London. Google Scholar14. DavidoffCushing LMH: Studies in acromegaly: VI. The disturbances of carbohydrate metabolism, Arch. Int. Med. 39: 751-779, 1927. CrossrefGoogle Scholar15. CoggeshallRoot CHF: Acromegaly and diabetes mellitus, Endocrinology 26 1-25, 1940. CrossrefGoogle Scholar16. CushingDavidoff HLM: Studies in acromegaly: IV. The basal metabolism, Arch. Int. Med. 39: 673-397, 1927. CrossrefGoogle Scholar17. Davis AC: The thyroid gland in 166 cases of acromegaly, Jr. Clin. Endocrinol. 1: 445-449, 1941. CrossrefGoogle Scholar18. Selye H: Textbook of endocrinology, 1948, Universite de Montreal, Montreal. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: MILTON R. HEJTMANCIK, M.D.; JAMES Y. BRADFIELDJR., M.D.; GEORGE R. HERRMANN, M.D., F.A.C.P.Affiliations: Galveston, Texas*Received for publication December 28, 1949.From the Cardiovascular Service, University of Texas School of Medicine Hospitals, Galveston, Texas.Supported in part by a grant-in-aid from the H. H. Weinert Fund for Cardiovascular Research. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySpecific FSTL1 polymorphism may determine the risk of cardiomyopathy in patients with acromegalyEchocardiographic findings in acromegaly: prevalence of concentric left ventricular remodeling in a large single-center cohortCardiac functions in children with growth hormone deficiency: Effects of one year of GH replacement therapyAcromegaly and Heart FailureRemisyonda akromegali hastalarında aortik stifness (sertliğin ) değerlendirilmesiSleep apnea and cardiovascular complications of the acromegaly. 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FROMMER, M.D., F.A.C.P.Myocardial blood flow and oxygen uptake in clinical and experimental cardiomegalyA SINGAPORE GIANT (GIGANTISM WITH ACROMEGALY): UNTREATED WITH LONG SURVIVALHeart muscle disease in acromegalyUncommon or commonly unrecognized causes of heart failureThe roentgen features of the cardiomyopathiesMetabolism of the heart in health and disease. Part IIIThe hand and the heartSome Radiological Aspects of AcromegalyExcessive growth and sex chromosome anomaliesCase 3-1963Diagnostik der intrakraniellen GeschwülsteAcromegalic gigantismHerz und Kreislauf bei Hypophysenvorderlappeninsuffizienz und nach HypophysektomieEXTREME CARDIAC ENLARGEMENT*CARL C. EPSTEIN, M.D., F.A.C.P.Die Keimdrüsen und ihre KrankheitenDas Herz bei endokrinen StörungenPathophysiologie, Klinik und Behandlung der Hypophysenadenome 1 June 1951Volume 34, Issue 6Page: 1445-1456KeywordsAcromegalyAutopsyCardiology and cardiovascular diseasesCardiovascular therapyHeartHeart diseasesHeart failureHospital medicineLongitudinal studiesResearch funding ePublished: 1 December 2008 Issue Published: 1 June 1951 PDF downloadLoading ...