TLR4 signal ablation attenuated neurological deficits by regulating microglial M1/M2 phenotype after traumatic brain injury in mice

Microglia Initiate Central Nervous System Innate and Adaptive Immune Responses through Multiple TLRs

Julie K. Olson, Stephen D. Miller · The Journal of Immunology · 2004 · 1.2K citations · Full text

Life Sciences, Immunology, Neuroscience +17

Toll-Like Receptor 4-Dependent Activation of Dendritic Cells by β-Defensin 2

Arya Biragyn, Pier Adelchi Ruffini, Cynthia A. Leifer et al. · Science · 2002 · 890 citations

Life Sciences, Immunology, Infectious Diseases +17

Receptor-Mediated Monitoring of Tissue Well-Being Via Detection of Soluble Heparan Sulfate by Toll-Like Receptor 4

Geoffrey B. Johnson, Gregory J. Brunn, Yuzo Kodaira et al. · The Journal of Immunology · 2002 · 651 citations

Life Sciences, Immunology, Molecular Biology +14

Trauma Mortality in Mature Trauma Systems: Are We Doing Better? An Analysis of Trauma Mortality Patterns, 1997–2008

Richard P. Dutton, Lynn G. Stansbury, Susan Leone et al. · The Journal of Trauma: Injury, Infection, and Critical Care · 2010 · 413 citations

Medicine, Emergency Medicine, Surgery +17

Toll-Like Receptor 4 on Nonhematopoietic Cells Sustains CNS Inflammation during Endotoxemia, Independent of Systemic Cytokines

Sumana Chakravarty, Miles Herkenham · Journal of Neuroscience · 2005 · 400 citations · Full text

Life Sciences, Immunology, Neuroscience +17