Regeneration of Cone Outer Segments Induced by CNTF

Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light.

M. M. LaVail, K Unoki, Douglas Yasumura et al. · Proceedings of the National Academy of Sciences · 1992 · 732 citations

Life Sciences, Neuroscience, Ophthalmology +16

Ciliary neurotrophic factor (CNTF) for human retinal degeneration: Phase I trial of CNTF delivered by encapsulated cell intraocular implants

Paul A. Sieving, Rafael C. Caruso, Weng Tao et al. · Proceedings of the National Academy of Sciences · 2006 · 592 citations · Full text

Medicine, Ophthalmology, Vision Science +10

Protection of mouse photoreceptors by survival factors in retinal degenerations.

Matthew M. LaVail, D Yasumura, Michael T. Matthes et al. · PubMed · 1998 · 498 citations

Medicine, Neuroscience, Ophthalmology +16

Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa.

Weng Tao, Rong Wen, Moses Goddard et al. · PubMed · 2002 · 330 citations

Medicine, Ophthalmology, Vision Science +16

Longitudinal Study of Cone Photoreceptors during Retinal Degeneration and in Response to Ciliary Neurotrophic Factor Treatment

Katherine E. Talcott, Kavitha Ratnam, S. Sundquist et al. · Investigative Ophthalmology & Visual Science · 2010 · 276 citations · Full text

Medicine, Ophthalmology, Surgery +17