Nano-Targeting of Mucosal Addressin Cell Adhesion Molecule-1 Identifies Bowel Inflammation Foci in Murine Model

Abstract

Anti-MAdCAM-1 functionalized nanoparticles detected active bowel inflammation foci, accurately following MAdCAM-1 expression pattern. These nanoconjugates could be a promising noninvasive imaging system for an early and accurate follow-up in patients affected by acute colitis.