The rs7903146 Variant in the <i>TCF7L2</i> Gene Increases the Risk of Prediabetes/Type 2 Diabetes in Obese Adolescents by Impairing β-Cell Function and Hepatic Insulin Sensitivity - Concepedia

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Publication | Open Access

The rs7903146 Variant in the <i>TCF7L2</i> Gene Increases the Risk of Prediabetes/Type 2 Diabetes in Obese Adolescents by Impairing β-Cell Function and Hepatic Insulin Sensitivity

DOI Full Paper Access

84

Citations

36

References

2017

Year

Catrina Cropano, Nicola Santoro, Leif Groop, Chiara Dalla Man, Claudio Cobelli, Alfonso Galderisi, Romy Kursawe, Bridget Pierpont, Martina Goffredo, Sonia Caprio

Abstract

The rs7903146 variant in the <i>TCF7L2</i> gene increases the risk of IGT/T2D in obese adolescents by impairing β-cell function, and hepatic insulin sensitivity predicts the development of IGT/T2D over time.

References

	Year	Citations

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