Chelerythrine Attenuates Renal Ischemia/Reperfusion-induced Myocardial Injury byActivating CSE/H2S via PKC/NF-κB Pathway in Diabetic Rats

Abstract

These findings suggest that CHE-pretreatment may exert a protective effect on the myocardium against RI/RMI by activating endogenous CSE/H2S via PKC/NF-κB pathway in STZ-induced diabetic rats. Further studies are needed defining underlying mechanisms.