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Erythrocyte Mean Corpuscular Volume (MCV) Correlation with Thiopurine Methyl Transferase (TPMT) Activity in Inflammatory Bowel Disease (IBD) Patients Receiving Azathioprine (AZA)/6-Mercaptopurine (6MP)
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2004
Year
InflammationTherapeutic Drug MonitoringIndividual PatientsFunctional Gastrointestinal DisorderMedicineImmunologyGastroenterologyPathologyLaboratory MedicineHematologyAutoimmunityAzathioprine/6-mercaptopurine TherapyPharmacotherapyClinical ChemistryMethyl TransferaseUlcerative ColitisPharmacologyThiopurine Methyl Transferase
Background: Azathioprine/6-mercaptopurine therapy leads to variable degree of change in the mean red cell corpuscular volume (MCV). This variability may be related to thiopurine methyl transferase (TPMT) activity of individual patients.