Evaluation of Vitamin D, Vitamin D Binding Protein Gene Polymorphism with Oxidant – Antioxidant Profiles in Chronic Obstructive Pulmonary Disease

Abstract

COPD patients had significantly lower plasma 25-OHD and were associated with significantly higher VDBP Gc1F-1S genotypes and Gc1F variants frequencies than controls. Low vitamin D levels and VDBP polymorphism may be important as diagnostic risk factors in the susceptibility to and severity of COPD.