Concepedia

Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Filgotinib, a Selective JAK‐1 Inhibitor, After Short‐Term Treatment of Rheumatoid Arthritis: Results of Two Randomized Phase IIa Trials

Frédéric Vanhoutte, Minodora Mazur, O.I. Voloshyn, Mykola Stanislavchuk, Annegret Van der Aa, Florence Namour, René Galien, Luc Meuleners, Gerben van ‘t Klooster

Arthritis & Rheumatology · 2017 · 75 citations · 25 references

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Abstract

Selective inhibition of JAK-1 with filgotinib shows initial efficacy in RA with an encouraging safety profile in these exploratory studies.

References

25

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

Frank C. Arnett, Steven M. Edworthy, D. Blöch et al. · Arthritis & Rheumatism · 1988 · 19.8K citations

Revised Criteria for the Classification of Rheumatoid Arthritis

Frank C. Arnett · Orthopaedic Nursing · 1990 · 7.7K citations

, , +10

Modified disease activity scores that include twenty-eight-joint counts development and validation in a prospective longitudinal study of patients with rheumatoid arthritis

M.L.L. Prevoo, Martin A. van't Hof, H. H. Kuper et al. · Arthritis & Rheumatism · 1995 · 6.1K citations

Measurement of patient outcome in arthritis

James F. Fries, Patricia W. Spitz, R. Guy Kraines et al. · Arthritis & Rheumatism · 1980 · 4.3K citations

, , +13

American college of rheumatology preliminary definition of improvement in rheumatoid arthritis

David T. Felson, Jennifer J. Anderson, Maarten Boers et al. · Arthritis & Rheumatism · 1995 · 2.8K citations