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Publication | Open Access

A reverse genetics system for avian coronavirus infectious bronchitis virus based on targeted RNA recombination

46

Citations

32

References

2017

Year

Abstract

Targeted RNA recombination allows for the generation of recombinant IBV strains that are not able to infect and propagate in continuous cell lines. The ability to introduce specific mutations holds promise for the development of rationally designed live-attenuated IBV vaccines and for studies into the biology of IBV in general.

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