Rat Limbal Niche Cells Prevent Epithelial Stem/Progenitor Cells From Differentiation and Proliferation by Inhibiting Notch Signaling Pathway In Vitro

Abstract

Rat LNCs prevent LESCs from differentiation and proliferation primarily via inhibiting the Notch signaling in vitro. Manipulating the Notch signaling pathway may help to preserve LESCs for corneal epithelial tissue engineering.