Phase I study of temsirolimus in combination with cetuximab in patients with advanced solid tumours

Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

Dos D. Sarbassov, Siraj M. Ali, Shomit Sengupta et al. · Molecular Cell · 2006 · 2.6K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +6

mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt

Kathryn O’Reilly, F. Rojo, Qing‐Bai She et al. · Cancer Research · 2006 · 2.6K citations · Full text

Medicine, Oncology, Pharmacology +16

<i>KRAS</i> Mutation Status Is Predictive of Response to Cetuximab Therapy in Colorectal Cancer

Astrid Lièvre, Jean‐Baptiste Bachet, Delphine Le Corre et al. · Cancer Research · 2006 · 2.2K citations

Medicine, Oncology, Pharmacology +17

Cetuximab for the Treatment of Colorectal Cancer

Derek J. Jonker, Chris J. O’Callaghan, Christos S. Karapetis et al. · New England Journal of Medicine · 2007 · 1.8K citations · Full text

Medicine, Oncology, Pharmacology +17

Cetuximab in the treatment of colorectal cancer.

Richard M. Goldberg, Alan P. Venook, Richard L. Schilsky · PubMed · 2004 · 1.5K citations

Medicine, Oncology, Pharmacology +10