<i>In vivo</i> and clinical application of strontium-enriched biomaterials for bone regeneration

Abstract

This review showed the safety and effectiveness of Sr-enriched biomaterials for stimulating bone formation and remodelling in animal models. The effect seems to increase over time and is impacted by the concentration used. However, included studies present a wide range of study methods. Future work should focus on consistent models and guidelines when developing a future clinical application of this element.<b>Cite this article:</b> N. Neves, D. Linhares, G. Costa, C. C. Ribeiro, M. A. Barbosa. <i>In vivo</i> and clinical application of strontium-enriched biomaterials for bone regeneration: A systematic review. <i>Bone Joint Res</i> 2017;6:366-375. DOI: 10.1302/2046-3758.66.BJR-2016-0311.R1.