Sorbistin, a new aminoglycoside antibiotic complex of bacterial origin. III. Structure determination.

MASATAKA KONISHI, S. Kamata, Takashi Tsuno, Kei-Ichi Numata, Hiroshi Tsukiura, TAKAYUKI NAITÔ, Hiroshi Kawaguchi

The Journal of Antibiotics · 1976 · 16 citations · 3 references

Concepts

Abstract

The structures of sorbistins A1, A2, B, C and D have been determined including stereo-chemistry. Sorbistins A1, A2 and B are composed of a 4-acyl-amino-4-deoxy-D-glucose and 1,4-diamino-1,4-dideoxy-D-sorbitol, the latter compound being hitherto undescribed in literature. Sorbistins C and D have the same aglycone of 1,4-diamino-1,4-dideoxy-D-sorbitol, which is linked with D-glucose and 4-amino-4-deoxy-D-glucose, respectively, through a glycosidic bond.

References

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