Trafficking and localisation to the plasma membrane of Na<sub>v</sub>1.5 promoted by the β2 subunit is defective due to a β2 mutation associated with Brugada syndrome - Concepedia

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Trafficking and localisation to the plasma membrane of Na<sub>v</sub>1.5 promoted by the β2 subunit is defective due to a β2 mutation associated with Brugada syndrome

21

Citations

44

References

2017

Year

Gemma Dulsat, Sònia Palomeras, Èric Cortada, Helena Riuró, Ramón Brugada, Marcel Vergés

Biology of the Cell

Abstract

Our findings add to the understanding of β2 role in Na<sub>v</sub> 1.5 trafficking and localisation, which must influence cell excitability and electrical coupling in the heart. This study will contribute to knowledge on development of arrhythmias.

References

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