Disrupted small-world brain functional network topology in male patients with severe obstructive sleep apnea revealed by resting-state fMRI

Abstract

Our results suggest that the high degree of local integration and integrity of the brain connections in OSA patients may be disrupted. The topological alterations of small-world properties may be the mechanism of cognitive impairment in OSA patients. In addition, σ, γ, and λ could be used as a quantitative physiological index for auxiliary clinical diagnoses.