Concepedia

Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase

Shira G. Ziegler, Carlos R. Ferreira, Elena Gallo MacFarlane, Ryan C. Riddle, Ryan E. Tomlinson, Emily Y. Chew, Ludovic Martin, Chen-Ting Ma, Eduard Sergienko, Anthony B. Pinkerton,

Science Translational Medicine · 2017 · 110 citations · 44 references

DOI

Concepts

Abstract

Ectopic calcification in PXE integrates both local and systemic perturbations of extracellular ATP metabolism and can be attenuated with a TNAP inhibitor.

References

44

Preparation of PCR-Quality Mouse Genomic DNA with Hot Sodium Hydroxide and Tris (HotSHOT)

Gary E. Truett, Peter S. Heeger, Randall L. Mynatt et al. · BioTechniques · 2000 · 1.8K citations · Full text

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Age-Related Changes in Trabecular Architecture Differ in Female and Male C57BL/6J Mice

Vaida Glatt, Ernesto Canalis, Lisa Stadmeyer et al. · Journal of Bone and Mineral Research · 2007 · 607 citations

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Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification

Frank Rutsch, Nico Ruf, Sucheta M. Vaingankar et al. · Nature Genetics · 2003 · 603 citations

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Mutations in ABCC6 cause pseudoxanthoma elasticum

Arthur A. Bergen, Astrid S. Plomp, Ellen J. Schuurman et al. · Nature Genetics · 2000 · 597 citations

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Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum

Olivier Le Saux, Zsolt Urbán, Cordula Tschuch et al. · Nature Genetics · 2000 · 540 citations · Full text

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