Prognostic factors for head and neck cancer of unknown primary including the impact of human papilloma virus infection

Lars Axelsson, Jan Nyman, Hedda Haugen-Cange, Mogens Bove, Leif Johansson, Shahin De Lara, Anikó Kovács, Eva Hammerlid

Journal of Otolaryngology - Head and Neck Surgery · 2017 · 51 citations · 28 references

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Abstract

Curatively treated HNCUP had good survival. HPV infection was common. Independent prognostic factors for survival were age over 70 years, HPV status and N3 stage. We recommend that HPV analysis should be performed routinely for HNCUP. Treatment with neck dissection and postoperative radiation or (chemo) radiation showed similar survival rates.

References

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