Organic Letters · 2017 · 16 citations · 51 references
Natural SciencesChemistryCatalysisGreen ChemistryOrganic ChemistryHeterocycle SynthesisHeterocyclic ChemistryMacrocycle SynthesisOrganic SynthesisRearrangement ReactionsRearrangement Techniques
A cascade reaction to build vinyl cyclobutanol rings through activation of vinyl epoxides by palladium, followed by 1,4-Brook rearrangement and intramolecular cyclization with a palladium complex of the resulting carbon anion, is described. Through this cascade reaction, several highly substituted cyclobutanol substrates were achieved in good yields with high stereoselectivities.
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Mechanisms of catalyst deactivation
Calvin H. Bartholomew · Applied Catalysis A General · 2001 · 3K citations