The distribution of positively charged residues in bacterial inner membrane proteins correlates with the trans‐membrane topology

Three-dimensional model of purple membrane obtained by electron microscopy

Richard A. Henderson, P.N.T. Unwin · Nature · 1975 · 2.3K citations

Natural Sciences, Biology, Biophysics +12

Intracellular protein topogenesis

Günter Blobel · Proceedings of the National Academy of Sciences · 1980 · 1.4K citations · Full text

Life Sciences, Biochemistry, Cell Biology +7

TnphoA: a transposon probe for protein export signals.

Colin Manoil, J Beckwith · Proceedings of the National Academy of Sciences · 1985 · 1K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +13

The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis

Donald M. Engelman, Thomas A. Steitz · Cell · 1981 · 880 citations

Natural Sciences, Biochemistry, Biophysics +14

Sequence of the lactose permease gene

Dagmar E. Büchel, Bruno Gronenborn, Benno Müller‐Hill · Nature · 1980 · 497 citations

Agriculture, Microbiology, Molecular Biology +12