Journal of Periodontology · 2017 · 34 citations · 38 references
The present study confirms that metformin suppresses LPS-enhanced IL-6, IL-1β, and TNF-α production in HGFs via increasing ATF3 expression.
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IL-6 is produced by osteoblasts and induces bone resorption.
Yoshiko Ishimi, Chisato Miyaura, Cheng Jin et al. · The Journal of Immunology · 1990 · 1.1K citations
Mechanism by which metformin reduces glucose production in type 2 diabetes.
Ripudaman S. Hundal, Martin Krššák, Sylvie Dufour et al. · Diabetes · 2000 · 1K citations · Full text
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