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Recent Advances in the Synthesis of Pyrazole Derivatives Using Multicomponent Reactions
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2017
Year
Combinatorial ChemistryMedicinal ChemistryDerivative (Chemistry)Bioorganic ChemistryVital Pyrazole DerivativesNatural SciencesMedicineDiversity-oriented SynthesisVaried Multicomponent/onepot ProtocolsOrganic ChemistryMicrowave IrradiationSynthetic ChemistryChemistryHeterocycle ChemistryPharmacologyPharmaceutical ChemistryRecent AdvancesDrug Discovery
Aim and Objective: In this review, we summarize the current state of varied multicomponent/onepot protocols for synthesis of vital pyrazole derivatives under varied conditions, including in absence and presence of catalysts, solvent and solvent-free conditions, and using other techniques such as microwave irradiation and ultrasonication. In broad sense, this review covers the publications up to 2015. Keywords: Pyrazoles, synthesis, multicomponent reactions, biological activity, green chemistry, medicinal chemistry.