Tumors of the skin. V. Local administration of anti-tumor agents to multiple superficial basal cell carcinomas.

Abstract

In a previous double blind placebo-controlled study (1), topical administration of several antitumor agents was found to alter the natural course of solitary basal cell carcinoma, including complete regression in a statistically significant number of lesions. Several studies on the effects of local administration of chemotherapeutic agents to tumors in the skin and subcutaneous tissues, previously reported from this group (2-7) and other investigators (8-12), indicated that further investigation is warranted. This paper reports the effects of local administration of anti-tumor agents on multiple superficial basal cell epitheliomas.