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Comparative Evaluation of αCD40 (2C10R4) and αCD154 (5C8H1 and IDEC-131) in a Nonhuman Primate Cardiac Allotransplant Model

DOIFull Paper Access

18

Citations

39

References

2017

Year

Natalie A. O’Neill, Tianshu Zhang, Gheorghe Braileanu, Wenji Sun, Xiangfei Cheng, Alena Hershfeld, Christopher Laird, Anthony Kronfli, Lindsay A. Hock, Siamak Dahi,
Transplantation

Abstract

In this model, CD154/CD40 axis blockade using IDEC-131 is an inferior immunomodulatory treatment than 5C8H1 or 2C10R4, which have similar efficacy to prolong graft survival and to delay cardiac allograft vasculopathy development and antidonor alloAb production during treatment.

References

YearCitations

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