A reductive aminase from Aspergillus oryzae

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

Christopher K. Savile, Jacob M. Janey, Emily C. Mundorff et al. · Science · 2010 · 1.7K citations

Engineering, Biocatalytic Asymmetric Synthesis, Organic Chemistry +17

Chiral Amine Synthesis – Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

Thomas C. Nugent, Mohamed El‐Shazly · Advanced Synthesis & Catalysis · 2010 · 880 citations

Enamide Reduction, Engineering, Chiral Amine Literature +13

Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades

Francesco G. Mutti, Tanja Knaus, Nigel S. Scrutton et al. · Science · 2015 · 404 citations · Full text

Engineering, Biochemistry, Natural Sciences +15

Engineering an Enantioselective Amine Oxidase for the Synthesis of Pharmaceutical Building Blocks and Alkaloid Natural Products

Diego Ghislieri, Anthony P. Green, Marta Pontini et al. · Journal of the American Chemical Society · 2013 · 363 citations

Combinatorial Chemistry, Engineering, Organic Chemistry +18

A platform for the discovery of new macrolide antibiotics

Ian B. Seiple, Ziyang Zhang, Pavol Jakubec et al. · Nature · 2016 · 344 citations · Full text

Antimicrobial Drug Discovery, Antibiotics, Medicine +8