Oral Glucocorticoid–Sparing Effect of Benralizumab in Severe Asthma

Abstract

Benralizumab showed significant, clinically relevant benefits, as compared with placebo, on oral glucocorticoid use and exacerbation rates. These effects occurred without a sustained effect on the FEV₁. (Funded by AstraZeneca; ZONDA ClinicalTrials.gov number, NCT02075255 .).