Medicinal uses and biological activities of Vitex negundo

Abstract

Vitex negundo Linn. is credited with innumerable medicinal activities like analgesic, anti-inflammatory, anticonvulsant, antioxidant, bronchial relaxant, hepatoprotective, etc. The ethanolic extract of leaves has been found safe as LD 50 dose (by oral route) of it was recorded in non-toxic dose range. Larger trials are required to prove its all activities before it is recommended in future for clinical use, but it carries a great potential to be developed as a drug by the pharmaceutical industry. In this paper general medicinal uses and pharmacological activities of various parts of the plant have been reviewed.