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Dose-dependent effect and pharmacokinetics of fexinidazole and its metabolites in a mouse model of human African trypanosomiasis

Human African TrypanosomiasisBiochemistryAntiparasitic AgentMedicineParasitic ProtozoaAfrican TrypanosomiasisPathologyDose-dependent EffectToxicologyMetabolomicsExperimental ToxicologyPharmacologyMouse ModelPharmacokineticsDrug DiscoveryDrug Resistance