Brain-derived Neurotrophic Factor Promotes Growth of Neurons and Neural Stem Cells Possibly by Triggering the Phosphoinositide 3-Kinase/ AKT/Glycogen Synthase Kinase-3β/β-catenin Pathway - Concepedia

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Brain-derived Neurotrophic Factor Promotes Growth of Neurons and Neural Stem Cells Possibly by Triggering the Phosphoinositide 3-Kinase/ AKT/Glycogen Synthase Kinase-3β/β-catenin Pathway

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References

2017

Year

Xing-Tong Li, Liang Zhang, Tongtong Wang, Jinwei Yang, Wei Ma, Shi-Kang Deng, Xianbin Wang, Yunfei Dai, Jianhui Guo, Liyan Li

CNS & Neurological Disorders - Drug Targets

Abstract

Our findings suggested that BDNF contributed to neuronal growth and proliferation and differentiation of NSCs in vitro by stimulating PI3K/AKT/GSK3β/β-catenin pathways.