Publication | Closed Access
A Convenient Strategy for Remote C–H Bond Halogenation of 8-Aminoquinolines in the C5 Position
12
Citations
3
References
2017
Year
EngineeringHeterocyclicConvenient StrategyFunctional GroupsNatural SciencesDiversity-oriented SynthesisC5 PositionOrganic ChemistryTransition-metal-free ConditionsOrganometallic CatalysisChemistryHeterocycle ChemistryHalogenationBiomolecular Engineering
A highly efficient and convenient strategy has been developed for remote C–H bond halogenation of 8-aminoquinolines in good to excellent yields under transition-metal-free conditions. The reaction tolerates a variety of functional groups and can potentially be scaled up.
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